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Table 7 Performance comparison of PROSITE patterns, Profile HMMs and SCFGs

From: A stochastic context free grammar based framework for analysis of protein sequences

 

Size

Method

Max F1

Pr

Rc

Rc| Pr = 1.0

PS00219

12

PROSITE

0.94

1.00

0.89

0.89

 

12

SCFG

1.00

1.00

1.00

1.00

PS00063

16

PROSITE

0.81

1.00

0.81

0.81

 

16

Profile HMM

0.95

1.00

0.91

0.91

 

16

SCFG

0.71

0.79

0.65

0.29

PS00307

7

PROSITE

0.52

0.36

0.94

0.94

 

25

Profile HMM

1.00

1.00

1.00

1.00

 

25

SCFG

0.91

1.00

0.84

0.84

MPI phosphatase

-

PROSITE

No PROSITE pattern

 

25

Profile HMM

0.96

1.00

0.92

0.92

 

25

SCFG

0.94

0.98

0.89

0.85

Zinc finger

10-26

PROSITE

Out of scope

 

26

Profile HMM

0.79

0.76

0.82

0.21

 

26

SCFG

0.81

0.75

0.87

0.21