Comparison of computational time of CM, R AVE N N A and pHMM searches for different riboswitch families. Red - CM, green - RAVE NN A, pink - pHMM. Time is represented on log scale. It shows that pHMMs are several 100 times faster than CM. 73 complete genomes from Refseq database with size ranging from 20 KB to 13 MB were used to calculate computing time for different approaches.