TY - JOUR AU - Van Nguyen, Hoa AU - Lavenier, Dominique PY - 2009 DA - 2009/10/12 TI - PLAST: parallel local alignment search tool for database comparison JO - BMC Bioinformatics SP - 329 VL - 10 IS - 1 AB - Sequence similarity searching is an important and challenging task in molecular biology and next-generation sequencing should further strengthen the need for faster algorithms to process such vast amounts of data. At the same time, the internal architecture of current microprocessors is tending towards more parallelism, leading to the use of chips with two, four and more cores integrated on the same die. The main purpose of this work was to design an effective algorithm to fit with the parallel capabilities of modern microprocessors. SN - 1471-2105 UR - https://doi.org/10.1186/1471-2105-10-329 DO - 10.1186/1471-2105-10-329 ID - Van Nguyen2009 ER -