Table 3 Performance of MOPHY in capturing the underlying evolutionary distances for simulated networks.
From: Phylogenetic analysis of modularity in protein interaction networks
Most Specific Modules | |||||||||
|---|---|---|---|---|---|---|---|---|---|
Diameter | |||||||||
2 | 3 | 4 | |||||||
Coverage | M OPHY | Random | p -value | M OPHY | Random | p -value | M OPHY | Random | p -value |
20% | 6.87** | 16.40 | 0.0020 | 6.84** | 15.85 | 0.0017 | 6.97** | 15.78 | 0.0019 |
40% | 6.81** | 16.14 | 0.0017 | 6.86** | 15.85 | 0.0017 | 7.01** | 15.53 | 0.0029 |
60% | 6.79** | 15.85 | 0.0017 | 6.86** | 15.41 | 0.0016 | 7.02** | 15.25 | 0.0026 |
Most Comprehensive Modules | |||||||||
Diameter | |||||||||
2 | 3 | 4 | |||||||
Coverage | M OPHY | Random | p -value | M OPHY | Random | p -value | M OPHY | Random | p -value |
20% | 8.89 | 11.72 | 0.2283 | 9.67 | 11.76 | 0.3512 | 10.83 | 11.82 | 0.6277 |
40% | 7.62* | 13.12 | 0.0277 | 8.44 | 11.61 | 0.2029 | 9.63 | 11.29 | 0.4922 |
60% | 6.70** | 14.93 | 0.0018 | 7.92 | 12.90 | 0.0529 | 8.96 | 11.51 | 0.3263 |