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Table 3 Performance of MOPHY in capturing the underlying evolutionary distances for simulated networks.

From: Phylogenetic analysis of modularity in protein interaction networks

Most Specific Modules
  Diameter
  2 3 4
Coverage M OPHY Random p -value M OPHY Random p -value M OPHY Random p -value
20% 6.87** 16.40 0.0020 6.84** 15.85 0.0017 6.97** 15.78 0.0019
40% 6.81** 16.14 0.0017 6.86** 15.85 0.0017 7.01** 15.53 0.0029
60% 6.79** 15.85 0.0017 6.86** 15.41 0.0016 7.02** 15.25 0.0026
Most Comprehensive Modules
  Diameter
  2 3 4
Coverage M OPHY Random p -value M OPHY Random p -value M OPHY Random p -value
20% 8.89 11.72 0.2283 9.67 11.76 0.3512 10.83 11.82 0.6277
40% 7.62* 13.12 0.0277 8.44 11.61 0.2029 9.63 11.29 0.4922
60% 6.70** 14.93 0.0018 7.92 12.90 0.0529 8.96 11.51 0.3263
  1. For each parameter setting, the nodal distance between the underlying tree and the tree reconstructed by MOPHY/randomized method is shown.