Binding residue prediction for 1R3E:A. Top row shows the front and bottom row shows the back of 1R3E:A (tRNA pseudouridine synthase. Left column: Protein structure and true binding site (yellow). Center column: Predicted binding site (yellow) by the Support Vector Machine (all features). Right column: Residue classification of 1R3E:A by the Support Vector Machine (all features), MCC 0.51, AUC 0.81, SN 71%, SP 90%. True positives are in yellow, true negatives are in gray, false positives are in blue and false negatives are in red. Diagrams are genereated with JMol http://jmol.sourceforge.net/.