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Figure 5 | BMC Bioinformatics

Figure 5

From: iQuantitator: A tool for protein expression inference using iTRAQ

Figure 5

Histograms showing errors in the log fold change estimate for a representative case without modifications (panels A and B) and a representative case with modifications (panels C and D) for iQuantitator (panels A and C) and the log-space averaging approach (panels B and D) provide a comparison of these methods. Inset graphs show the complete histogram for each case and main plots limit the y axis to 20 to make the proteins with larger errors more visible. Without modifications, both methods give similar results, with modifications the mean square error for iQuantitator is noticeably lower due to a relatively few proteins with large fold change errors in the log space averaging approach.

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