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Table 1 Summary of simulated data sets produced as described in the text and results of analysis using both iQuantitator and log-space averaging.

From: iQuantitator: A tool for protein expression inference using iTRAQ

       iQuantitator Mean of 116/117 and 114/115
Simulated Data Set Proteins Peptides Spectra Peptides per Protein Single Hit Proteins Mean Error Mean SE Median SE Mean Error Mean SE Median SE
Case 1 1034 4776 6938 4.6 494 -0.004 0.009 0.004 0.043 0.012 0.006
Case 2 1049 4452 6359 4.2 530 0.002 0.009 0.004 -0.020 0.010 0.005
Case 3 1061 4958 7049 4.7 514 0.006 0.010 0.004 0.004 0.011 0.005
Case 4 1032 4791 6923 4.6 492 0.005 0.008 0.003 -0.004 0.009 0.004
Average        0.009 0.004   0.011 0.005
With Mods 1 1055 4784 6911 4.5 515 -0.002 0.037 0.011 -0.013 0.140 0.011
With Mods 2 1026 4744 6776 4.6 507 0.003 0.042 0.010 -0.026 0.194 0.011
With Mods 3 1052 4769 6830 4.5 511 0.003 0.038 0.010 -0.008 0.114 0.011
With Mods 4 1066 4770 6869 4.5 516 -0.001 0.042 0.010 -0.015 0.199 0.011
Average 1050 4756 6832 5 510   0.040 0.010   0.162 0.011
Multi-Experiment 1321 6762 13534 5.1 620 -0.009 0.005 0.005 -0.004 0.005 0.005