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Table 2 Inference results for PCR based reporter assay simulated data

From: Bayesian inference of biochemical kinetic parameters using the linear noise approximation

Parameter Prior Value Estimate 1 Estimate 2
γ R Exp(1) 0.44 0.45 (0.35-0.60) 0.46 (0.42-0.50)
λ Exp(100) 1.00 1.07 (0.90-1.22) 1.01 (0.95-1.05)
b 0 Exp(100) 15.00 13.13 (10.20-15.87) 14.91 (13.86-15.77)
b 1 Exp(1) 0.40 0.29 (0.14-0.51) 0.43 (0.32-0.54)
b 2 Exp(1) 0.40 0.32 (0.12-0.93) 0.32 (0.21-0.43)
b 3 Exp(10) 7.00 7.05 (6.39-7.63) 6.99 (6.76-7.15)
b 4 Exp(100) 3.00 2.97 (2.00-4.18) 3.10 (2.76-3.43)
μ 0 Exp(100) 6.76 6.90 (5.79-7.69) 6.55 (6.14-6.85)
Exp(100) 6.76 3.52 (0.01-8.99) 7.59 (5.44-9.49)
  1. Parameter values used to generate data, prior distributions used for estimation, posterior median estimates together with 95% credibility intervals. Estimate 1, Estimate 2 columns relate to small (l = 5, n = 50) and large (l = 100, n = 50) sample sizes. Variance of the measurement was assumed to be known = 4. Estimated rates are per hour.