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Table 2 Effective inhibitor concentrations necessary to kill Trypanosoma brucei.

From: TIde: a software for the systematic scanning of drug targets in kinetic network models

  noncompetitive uncompetitive competitive
Glucose transport 1.09 1.27 6.13
Phosphoglycerate mutase 1.81 1.81 > 10000
Glyceraldehyde-3-p. dehydr. 2.89 5.32 6.17
Glycerol-3-p. dehydr. 3.79 3.88 253
Enolase 6.4 6.4 > 10000
Aldolase 8.14 8.36 319
  1. Shown are the concentrations required to reduce the flux through the upper glycolysis by 50% for different inhibition types and targets.