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Figure 3 | BMC Bioinformatics

Figure 3

From: Prediction of protein-protein interaction types using association rule based classification

Figure 3

2D plots for pairs of association rules. These plot data points by pairs of association rules. X and Y axes are a pair of rules and each of them have two boolean values. 0 represents negative data points not meeting with a rule of each axis and 1 represents for positive data points meeting with the rule. The data points on the upper left corner meet a rule used for Y axis and the data points on the down right corner meet a rule used for X axis. The points on the upper right corner meet with both rules used for X and Y axes. Plots in Figure 3(a), (b), and (c) characterize distribution of inhibitors in enzyme-inhibitors interactions. Rule 28 is used for X axis in plots (a), (b) and (c). Rules 1, 3 and 38 are used for the Y axis in those plots. (a) represents an example for a pair of rules both including SSE information (e.g. helix and loop content). (b) and (c) show examples for combination of SSE content information (Rule 28: "Nohelix ") with other properties (e.g. SCOPClass, number of atoms and etc.). Plot (b) (Rule 3 versus Rule 28) is identical to the plot generated by Rule 29. Enzymes interacting with a group of inhibitors characterized by (a), (b), and (c) are featured by in Figure 3(e), and (f). Enzymes and inhibitors described by Rules 40 and 29 respectively are plotted in (d) where there is no point matching with both rules. Plot (d) reflects proper interpretation of association rules regarding interactions between enzymes and inhibitors.

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