Figure 4From: Prediction of hot spot residues at protein-protein interfaces by combining machine learning and energy-based methodsPredicted versus observed changes in binding free energy ΔΔ G. In blue are the predictions from SVM regression, in red those from Robetta. The continuous lines correspond to linear fits between ΔΔG calc and ΔΔG obs , colour coded as the predictions (the respective equations are reported in the legend box).Back to article page