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Table 3 Weight of energy terms in the scoring function

From: Prediction of hot spot residues at protein-protein interfaces by combining machine learning and energy-based methods

Feature (energy term) Weight in SVM Weight in TSVM
Side-chain van der Waals 0.29 ± 0.05 0.37 ± 0.08
Side-chain hydrogen bond 0.15 ± 0.01 0.24 ± 0.03
Side-chain electrostatics 0.07 ± 0.03 0.08 ± 0.02
Side-chain desolvation 0.22 ± 0.01 0.19 ± 0.05
Environment van der Waals 0.17 ± 0.01 0.12 ± 0.04
Environment hydrogen bond 0.22 ± 0.04 0.24 ± 0.03
Environment electrostatics 0.07 ± 0.02 0.02 ± 0.03
Environment desolvation 0.12 ± 0.04 0.16 ± 0.04
Threshold 0.31 ± 0.07 0.90 ± 0.06
  1. We report the absolute value of the weight associated to each feature in the scoring function as determined by SVM and TSVM, together with the threshold that defines the decision boundary.