Mutated amino acid | In data set | Hot spots (ΔΔG≥ 2 kcal/mol) | Enrichment in hot spots | |||
---|---|---|---|---|---|---|
 | (Number) | (%) | (Number) | (%) (a) | (%) (b) |  |
Arg | 33 | 9.46 | 7 | 21.21 | 8.64 | 0.91 |
Asn | 22 | 6.30 | 6 | 27.27 | 7.41 | 1.18 |
Asp | 29 | 8.31 | 9 | 31.03 | 11.11 | 1.34 |
Cys | 1 | 0.29 | 0 | 0.00 | 0.00 | 0.00 |
Gln | 21 | 6.02 | 2 | 9.52 | 2.47 | 0.41 |
Glu | 31 | 8.88 | 5 | 16.13 | 6.17 | 0.69 |
His | 13 | 3.72 | 1 | 7.69 | 1.23 | 0.33 |
Ile | 15 | 4.30 | 4 | 26.67 | 4.94 | 1.15 |
Leu | 10 | 2.87 | 1 | 10.00 | 1.23 | 0.43 |
Lys | 32 | 9.17 | 11 | 34.38 | 13.58 | 1.48 |
Met | 2 | 0.57 | 0 | 0.00 | 0.00 | 0.00 |
Phe | 11 | 3.15 | 2 | 18.18 | 2.47 | 0.78 |
Ser | 28 | 8.02 | 1 | 3.57 | 1.23 | 0.15 |
Thr | 24 | 6.88 | 1 | 4.17 | 1.23 | 0.18 |
Trp | 23 | 6.59 | 9 | 39.13 | 11.11 | 1.69 |
Tyr | 44 | 12.61 | 20 | 45.45 | 24.69 | 1.96 |
Val | 10 | 2.87 | 2 | 20.00 | 2.47 | 0.86 |