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Table 1 Reference databases used for data retrieval during the investigation

From: Elucidation of functional consequences of signalling pathway interactions

Database

Description

URL

Statistics

Data extracted

Uniprot

[20]

comprehensive, high-quality and freely accessible resource of protein sequence and functional information.

http://www.uniprot.org

220,325 entries

function,, post-translation modification, location, developmental stage, etc.

I2d

[21]

on-line database of known and predicted mammalian and eukaryotic protein-protein interactions

http://ophid.utoronto.ca/

424,066 entries (92,561 for human)

protein interaction

Reactome

[22]

curated resource of core pathways and reactions in human biology.

http://www.reactome.org

928 pathways for human

Pathway

PID

[23]

curated pathway and interactions

http://pid.nci.nih.gov/

133 pathways

Pathway