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Table 1 Reference databases used for data retrieval during the investigation

From: Elucidation of functional consequences of signalling pathway interactions

Database Description URL Statistics Data extracted
Uniprot
[20]
comprehensive, high-quality and freely accessible resource of protein sequence and functional information. http://www.uniprot.org 220,325 entries function,, post-translation modification, location, developmental stage, etc.
I2d
[21]
on-line database of known and predicted mammalian and eukaryotic protein-protein interactions http://ophid.utoronto.ca/ 424,066 entries (92,561 for human) protein interaction
Reactome
[22]
curated resource of core pathways and reactions in human biology. http://www.reactome.org 928 pathways for human Pathway
PID
[23]
curated pathway and interactions http://pid.nci.nih.gov/ 133 pathways Pathway