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Table 12 Frequent components linking E2F1_HUMAN to the p53 network

From: Elucidation of functional consequences of signalling pathway interactions

Connector protein Frequency Protein in p53 Additional information of connector proteins
P53_HUMAN 2 CDN1A_HUMAN Cellular tumor antigen p53
CBP_HUMAN 2 MDM2_HUMAN CREB-binding protein
RB_HUMAN 2 CDN1A_HUMAN Retinoblastoma-associated protein
TIP60_HUMAN 1 MDM2_HUMAN Histone acetyltransferase HTATIP
SKP2_HUMAN 1 CDN1A_HUMAN S-phase kinase-associated protein 2
PARP1_HUMAN 1 CDN1A_HUMAN Poly [ADP-ribose] polymerase 1
ATM_HUMAN 1 MDM2_HUMAN Serine-protein kinase ATM
(Involved in 2 processes: Cell Cycle Checkpoints; DNA Repair)
MDM4_HUMAN 1 MDM2_HUMAN Protein Mdm4
CHK2_HUMAN 1 MDM2_HUMAN Serine/threonine-protein kinase Chk2
(Involved in 3 processes: Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Cell Cycle)
CDK3_HUMAN 1 CDN1A_HUMAN Cell division protein kinase 3