Figure 9
From: An empirical Bayesian approach for model-based inference of cellular signaling networks
Normalized error of the model predictions stratified by study. The distribution in the sum of the normalized error between the calibration data and the model predictions is shown for each study used in the analysis. (A) Total ErbB1 expression [20], (B) total phosphorylated ErbB1 [18], (C) total phosphorylated ErbB1 [31], (D) total phosphorylated ErbB1 [30], (E) total Grb2 attached to ErbB1 [18], (F) total Grb2 attached to Shc [18], (G) total Sos attached to ErbB1 [30], (H) phosphorylated Shc [18], (I) phosphorylated Shc [31], (J) phosphorylated Shc [22], (K) phosphorylated PLC-γ [31], and (L) activated Ras (Ras-GTP) [30]. Distributions for the three chains are shown in different colors: Chain 1 (Blue), Chain 2 (Black), and Chain 3 (Red).