Table 3 Functional analysis for DE genes at Nfkb1^-/- 180 mins from different normalization strategies

Source

Term

Count

FDR

Count

FDR

GOTERM_BP_ALL

immune system process

19

0.002

29

8.2E-5

GOTERM_BP_ALL

immune response

15

0.001

22

1.1E-4

SP_PIR_KEYWORDS

cytokine

9

0.01

13

3.3E-4

GOTERM_BP_ALL

cytokine metabolic process

4

0.96

9

0.005

GOTERM_BP_ALL

cytokine biosynthetic process

4

0.96

9

0.006

INTERPRO

Fos transforming protein

3

1.0

5

0.006

GOTERM_BP_ALL

cytokine production

5

0.88

10

0.01

GOTERM_BP_ALL

leukocyte activation

7

0.92

13

0.01

GOTERM_BP_ALL

hemopoietic or lymphoid organ development

7

0.89

14

0.01

GOTERM_BP_ALL

regulation of cytokine biosynthetic process

3

1.0

8

0.011

GOTERM_BP_ALL

immune system development

7

0.91

14

0.013

GOTERM_BP_ALL

cell activation

7

0.93

13

0.013

GOTERM_BP_ALL

hemopoiesis

7

0.94

13

0.014

GOTERM_BP_ALL

positive regulation of translation

3

1.0

7

0.014

GOTERM_BP_ALL

positive regulation of cellular biosynthetic process

3

1.0

7

0.019

KEGG_PATHWAY

Cytokine-cytokine receptor interaction

10

0.056

14

0.027

GOTERM_MF_ALL

cytokine activity

9

0.16

13

0.036

SP_PIR_KEYWORDS

glycoprotein

36

0.017

51

0.18