Figure 4
From: SitesIdentify: a protein functional site prediction tool
An example of differential site prediction between asymmetric and biological unit structures. The active site predicted for the asymmetric unit of 1b6t (phosphopantetheine adenylyltransferase) is reasonably close to the bound ligand shown in part A. The biological unit is formed by a cyclical arrangement of the asymmetric unit and when SitesIdentify is run on this structure it incorrectly identifies the central void as the enzyme active site (part B).