Skip to main content

Table 4 Sensitivity of co-evolution detection methods on InterPro profile pairs

From: Comparison of eukaryotic phylogenetic profiling approaches using species tree aware methods

Positive pair set Presence/absence profiling Group size profiling
  DPCP WRUNS GSHGT Pars GSCOR Pars GSHGT GeneT GSCOR GeneT
Unweighted negative control (TNUW)
TPCoPW 11.0% 9.8% 13.1% 18.7% 18.8% 31.9%
TPPPI 3.1% 3.3% 27.5% 34.4% 39.7% 63.7%
Weighted negative control (TNW)
TPCoPW 12.0% 11.9% 9.2% 13.9% 11.7% 14.4%
TPPPI 3.5% 3.9% 21.6% 26.5% 29.2% 42.4%