Figure 8
From: Modeling lymphocyte homing and encounters in lymph nodes
In silico experiment: the role of lymphocyte exit control. Number of Ag-specific duplicating lymphocytes with (dashed lines) and without (solid lines) S1P1 exit control. Results show the average number of duplicating TH (panel A) and B (panel B) cells. Blocking S1P1 downexpression, the magnitude of the immune response is greatly reduced.