Figure 6

Eukaryotic signal transduction: The Jak-STAT signalling pathway. Proteins are represented by their domain architectures shown as a series of rectangles, one for each domain. The labelled domains found in the Homo sapiens graph cluster (Figure 1) include SH2 (blue), PK-like (red), PH (pink), SH3 (green), RasGEF (turquoise), ARM (magenta). The arrows illustrate the Jak-STAT signalling pathway (derived from the KEGG database).