|
MHC
|
Data Size
|
SMM
|
SMMPMBEC
|
NetMHC
|
|---|
|
H-2_Db
|
303
|
0.909
|
0.901
|
0.933
|
|
H-2_Dd
|
85
|
0.813
|
0.837
|
0.925
|
|
H-2_Kb
|
223
|
0.811
|
0.833
|
0.850
|
|
H-2_Kd
|
176
|
0.928
|
0.931
|
0.939
|
|
H-2_Kk
|
164
|
0.772
|
0.793
|
0.790
|
|
H-2_Ld
|
102
|
0.932
|
0.942
|
0.977
|
|
HLA_A-0101
|
1157
|
0.977
|
0.977
|
0.982
|
|
HLA_A-0201
|
3089
|
0.946
|
0.946
|
0.957
|
|
HLA_A-0202
|
1447
|
0.898
|
0.899
|
0.900
|
|
HLA_A-0203
|
1443
|
0.916
|
0.916
|
0.921
|
|
HLA_A-0206
|
1437
|
0.913
|
0.916
|
0.927
|
|
HLA_A-0301
|
2094
|
0.927
|
0.928
|
0.937
|
|
HLA_A-1101
|
1985
|
0.938
|
0.939
|
0.951
|
|
HLA_A-2301
|
104
|
0.793
|
0.840
|
0.852
|
|
HLA_A-2402
|
197
|
0.803
|
0.801
|
0.825
|
|
HLA_A-2403
|
254
|
0.919
|
0.932
|
0.918
|
|
HLA_A-2601
|
672
|
0.916
|
0.924
|
0.956
|
|
HLA_A-2902
|
160
|
0.912
|
0.916
|
0.935
|
|
HLA_A-3001
|
669
|
0.935
|
0.941
|
0.947
|
|
HLA_A-3002
|
92
|
0.878
|
0.830
|
0.744
|
|
HLA_A-3101
|
1869
|
0.925
|
0.925
|
0.928
|
|
HLA_A-3301
|
1140
|
0.923
|
0.925
|
0.915
|
|
HLA_A-6801
|
1141
|
0.885
|
0.885
|
0.883
|
|
HLA_A-6802
|
1434
|
0.899
|
0.899
|
0.899
|
|
HLA_A-6901
|
833
|
0.867
|
0.880
|
0.880
|
|
HLA_B-0702
|
1262
|
0.959
|
0.960
|
0.965
|
|
HLA_B-0801
|
708
|
0.932
|
0.956
|
0.955
|
|
HLA_B-1501
|
978
|
0.937
|
0.940
|
0.941
|
|
HLA_B-1801
|
118
|
0.881
|
0.880
|
0.838
|
|
HLA_B-2705
|
969
|
0.936
|
0.941
|
0.938
|
|
HLA_B-3501
|
736
|
0.883
|
0.889
|
0.875
|
|
HLA_B-4002
|
118
|
0.832
|
0.843
|
0.754
|
|
HLA_B-4402
|
119
|
0.731
|
0.739
|
0.778
|
|
HLA_B-4403
|
119
|
0.757
|
0.753
|
0.763
|
|
HLA_B-4501
|
114
|
0.825
|
0.866
|
0.862
|
|
HLA_B-5101
|
244
|
0.876
|
0.895
|
0.886
|
|
HLA_B-5301
|
254
|
0.889
|
0.885
|
0.899
|
|
HLA_B-5401
|
255
|
0.923
|
0.935
|
0.903
|
|
HLA_B-5701
|
59
|
0.826
|
0.843
|
0.826
|
|
HLA_B-5801
|
988
|
0.942
|
0.945
|
0.961
|
|
Mamu_A-01
|
525
|
0.855
|
0.854
|
0.861
|
|
Mamu_A-02
|
283
|
0.765
|
0.783
|
0.809
|
|
Mamu_A-11
|
468
|
0.883
|
0.894
|
0.894
|
|
Mamu_B-01
|
205
|
0.949
|
0.956
|
0.967
|
|
Mamu_B-17
|
300
|
0.934
|
0.943
|
0.954
|
|
Patr_B-0101
|
132
|
0.964
|
0.975
|
0.969
|
|
average AUC
| |
0.887
|
0.894
|
0.897
|
|
t-test|SMM
| |
NA
|
0.001
|
0.057
|
|
t-test|NetMHC
| |
0.057
|
0.470
|
NA
|
- For each MHC-specific binding data set, 5-fold cross validation was carried out using one of the four methods listed. Area-Under-Curve (AUCs) from the 5-fold cross validations are presented here. Also shown are p-values of average AUC values calculated using Student's t-test (2-tail, paired) with respect to the SMM and NetMHC prediction methods.
