Protein-protein docking using region-based 3D Zernike descriptors

BMC Bioinformatics

Table 5 Parameters computed for the four scoring terms.

Number of Terms	Parameter type	3DZD-Normal Reward	3DZD-Normal Penalty	Buried Surface Area	Excluded Volume
4	Weight	2.39	15.85	-0.33	0.97
	Offset value	12.81	30.68	2525.13	751.44
2	Weight	-	-	0.653	-3.43
	Offset value	-	-	928.7	69.52

The parameters, the weights and offset values are calculated based on the training set of 29 bound-bound protein complexes for the four terms (Eqns. 6, 7 & 8) and for the two terms (Eqns. 7 & 8). Results for individual protein complexes are shown in Table 2.

ISSN: 1471-2105