Figure 2
From: Exploring complex miRNA-mRNA interactions with Bayesian networks by splitting-averaging strategy
Various miRNA-mRNA interactions in comparative study. Three types of observed miRNA-mRNA interactions are: i) miRNAs down-regulate mRNAs (a, b); ii) miRNAs up-regulate mRNAs (c, d); and iii) miRNAs down-regulate mRNAs in one category, but up-regulation appears in another category (e, f). Subtle interactions in (e) and (f) are unrevealing if the analysis ignores the sample categories. Our designed method is able to uncover all types of interactions.