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Table 5 Gene TP53 (lung cancer data).

From: The impact of measurement errors in the identification of regulatory networks

Association

t(β standard )

t(β corrected )

t(β standard ) -t(β corrected )

p53 → mdm2

-2.2550

-2.1250

-0.1299

p53 → fas

-3.3547

-3.0059

-0.3487

p53 → bax

5.2148

4.5290

0.6859

p53 → map4

2.8486

3.0243

-0.1757

mdm2 → fas

-1.5495

-1.5002

-0.0493

mdm2 → bax

0.1880

0.4716

-0.2836

mdm2 → map4

-0.8153

-0.2766

-0.5387

fas → bax

0.0987

0.5746

-0.4759

fas → map4

2.5776

2.6374

-0.0598

bax → map4

-0.3538

-0.7187

0.3650

  1. ; . The direction of the arrows means the direction of regression, i.e., in the head of the arrow is the predictor and in the tail of the arrow is the response variable. Since it is not a time series data, the t statistics are equal independent of the direction of regression, in other words, the t statistics of xy or yx are equal.