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Table 1 Results for protein disorder predictors that participated in CASP8 on 117 targets.

From: PreDisorder: ab initio sequence-based prediction of protein disordered regions

Disorder Predictor

ROC Score

Weighed Score

Total Res.

Pos. Sens.

Pos. Spec.

Neg. Sens.

Neg. Spec.

Sens. Prod.

F-meas.

MULTICOM

0.879

6.89

25148

0.532

0.619

0.973

0.962

0.518

0.572

DISOclust

0.862

7.822

24021

0.753

0.248

0.813

0.976

0.612

0.373

fais-server

0.861

6.613

24021

0.522

0.533

0.963

0.961

0.503

0.528

MULTICOM-CMFR*

0.859

8.06

25431

0.724

0.299

0.859

0.974

0.622

0.423

3Dpro*

0.855

4.826

23934

0.378

0.727

0.988

0.949

0.373

0.497

GS-MetaServer

0.852

5.356

24976

0.41

0.711

0.986

0.953

0.404

0.52

mariner1*

0.846

7.469

23148

0.622

0.396

0.923

0.968

0.574

0.484

Distill-Punch*

0.846

0.798

23311

0.067

0.75

0.998

0.93

0.067

0.123

Metaprdos

0.842

6.431

22363

0.505

0.539

0.966

0.961

0.488

0.522

Distill-Punch*

0.839

0.823

23730

0.063

0.881

0.999

0.93

0.063

0.118

CBRC_POODLE*

0.839

6.259

24021

0.522

0.403

0.937

0.96

0.489

0.455

GeneSilicoMeta

0.839

6.338

24976

0.489

0.627

0.976

0.959

0.478

0.55

DISOPRED*

0.831

6.497

24021

0.522

0.485

0.955

0.961

0.498

0.503

Biomine*

0.825

6.394

23472

0.517

0.47

0.952

0.96

0.492

0.493

OnD-CRF*

0.82

5.214

24021

0.47

0.31

0.914

0.955

0.429

0.373

Spritz*

0.791

5.431

24021

0.434

0.514

0.966

0.954

0.42

0.471

GSMetaDisorder

0.772

6.31

24504

0.579

0.289

0.88

0.961

0.51

0.386

Distill*

0.758

5.637

24021

0.671

0.173

0.738

0.965

0.495

0.276

LEE-SERVER*

0.741

3.595

21955

0.31

0.449

0.968

0.943

0.3

0.367

  1. Results of our evaluation of all the protein disorder predictors ranked by ROC Score (AUC). Total Res. represents the total number of residues predicted. Pos. Spec. and Neg. Spec. are the positive and negative specificities. Pos. Sens. and Neg. Sens. are the positive and negative sensitivities. F-meas. is the F-Measure of the positive sensitivity and positive specificity and Sens. Prod. is the product of the positive sensitivity and negative sensitivity. * denotes ab initio methods. MULTICOM-CMFR is the predictor name of PreDisorder in CASP8.