PreDisorder: ab initio sequence-based prediction of protein disordered regions

BMC Bioinformatics

Table 3 Results for protein disorder predictors that participated in CASP8 on the 97 x-ray targets.

Disorder Predictor	ROC Score	Weighed Score	Total Res.	Sens.	Spec.	Sens. Prod.	F-measure.
MULTICOM	0.887	7.021	23253	0.534	0.981	0.523	0.610
DISOclust	0.868	8.165	22420	0.758	0.823	0.624	0.397
fais-server	0.867	6.699	22420	0.523	0.969	0.506	0.555
MULTICOM-CMFR*	0.865	8.355	23536	0.721	0.873	0.630	0.455
3Dpro*	0.862	4.745	22523	0.375	0.990	0.372	0.507
GS-MetaServer	0.861	5.343	23201	0.411	0.991	0.407	0.541
Mariner1*	0.857	7.679	21547	0.623	0.933	0.582	0.518
Distill-Punch*	0.856	0.554	21710	0.069	0.999	0.069	0.128
CBRC_POODLE*	0.848	6.430	22420	0.523	0.949	0.496	0.493
GeneSilicoMeta	0.848	6.399	23201	0.490	0.982	0.481	0.579
Metaprdos	0.846	6.467	20762	0.507	0.968	0.491	0.536
DISOPRED*	0.837	6.571	22420	0.521	0.961	0.501	0.528
Biomine*	0.829	6.506	21983	0.519	0.959	0.498	0.522
OnD-CRF*	0.822	5.181	22420	0.471	0.913	0.430	0.379
Spritz*	0.800	5.478	22420	0.440	0.968	0.426	0.486
GSMetaDisorder	0.778	6.492	22850	0.576	0.894	0.515	0.417
Distill*	0.761	5.822	22420	0.670	0.746	0.499	0.289
LEE-SERVER*	0.749	3.438	20271	0.309	0.971	0.300	0.379

ISSN: 1471-2105