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Figure 1 | BMC Bioinformatics

Figure 1

From: ReseqChip: Automated integration of multiple local context probe data from the MitoChip array in mitochondrial DNA sequence assembly

Figure 1

Concept of multiple local context probes. (A) Three probe sets for 3 different sequence contexts are shown for one strand only. If an individual's (Ind) genome contains a nucleotide position different from the reference (rCRS) within 12 nucleotide positions (nps) on either side of the interrogated position, only one of the alternative probes in the lower right corner will yield a strong hybridization signal. (B) Section of an alignment of additional fragments to reference sequence (left-most column). Due to the specified settings only fragments marked by a star fulfil the required reliability of no N-calls within 3 nps on either side of the interrogated position.

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