Figure 2

Performance of a 14 feature linear model of intrinsic nucleosome sequence preference. (A) Scatter plot vs. test set (yeast chromosomes 10-16), shown as a heat-map. Axis values are log₂ normalized nucleosome occupancy (see Methods). (B) Model scores (probabilistic[8] and linear) and in vivo and in vitro nucleosome occupancy[8] within a 20 kb region of chromosome 14. (C) and (D) Correlation of the 14 feature model score with measured in vivo nucleosome occupancy in yeast (C) and with the Kaplan model across chr10-16 (test set) (D).