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Table 4 The English translations of the hypotheses generated from the set of 21 positive examples.

From: Predicting functional upstream open reading frames in Saccharomyces cerevisiae

A uORF has functional role if it satisfies at least one of the following rules.
1. the main gene is regulated under butanol stress and the product of the main gene is involved in nucleic acid binding;
2. the uORF is conserved in two other species, the main gene is localised in intracellular (or protoplasm), and the UTR length > = 463;
3. the uORF is conserved in three other species and the main gene is localised in intracellular (or protoplasm);
4. its length < = 7 and the product of the main gene is involved in nucleic acid binding;
5. the base in position +4 relative to the uORF's start codon is 'G' and the main gene is involved in regulation of biological process;
6. its length < = 6, the main gene is localised in intracellular (or protoplasm), and the main gene is involved in regulation of biological process;
7. the uORF is conserved in two other species, the main gene is not regulated under low concentration of H2O2, the main gene is localised in intracellular (or protoplasm), and the UTR length > = 244;
8. the product of the main gene is involved in translation regulator activity.