Figure 5

Comparison of the residues constituting ACT_CENT in cytochrome P450 2B4 and a model generated in a recapitulation experiment. In the left panel, the active site of cytochrome P450 (1po5) is plotted; in the right panel, the active site of the best model generated by TransCent is shown. The RMSD of the 23 recapitulated residues is 1.0 Å. Color code of side chains, which are depicted as sticks: (Arg, His, Lys), blue; (Asp, Glu), red; (Asn, Cys, Gln, Ser, Thr, Tyr), yellow. Hydrophobic resides are plotted in grey, the heme group is shown in green. Fig. 5 and 6 were created using Accelrys DS Visualizer 2.0 http://accelrys.com.