Table 1 Number of the active compounds for each target used in this study
From: An effective docking strategy for virtual screening based on multi-objective optimization algorithm
Target | MW Cutoff | No. Actives | No. Selected | Range RB (Mean) | Theoretical Maximum of Enrich Factor |
|---|---|---|---|---|---|
Thrombin | 200–600 | 847 | 646 | 4–29 (12.4) | 16.47 |
ER | 200–600 | 134 | 105 | 3–17 (8.5) | 96.23 |
COX-2 | 200–600 | 698 | 695 | 0–17 (4.0) | 15.39 |
Random database | 200–600 |  | 10000 | 0–35 (4.5) |  |