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Table 11 Comparison of reduced alphabets in terms of the ratio of exposed residues in the dataset by AA type Trans. = number of transitions between groups.

From: Automated Alphabet Reduction for Protein Datasets

Amino Acid

Exposed ratio

DualRMI

WW5

SR5

MU4

MM5

C

12.8%

1

1

1

1

1

I

15.4%

1

1

1

1

2

F

15.9%

1

1

1

2

2

L

19.5%

1

1

1

1

2

V

20.3%

1

1

1

1

2

W

21.3%

1

1

1

2

2

M

23.2%

1

1

1

1

2

Y

25.6%

1

1

1

2

2

A

33.6%

2

2

2

3

3

G

43.5%

3

3

3

3

3

H

43.8%

3

2

2

4

4

T

47.1%

3

2

2

3

5

S

48.0%

3

4

2

3

5

P

55.1%

4

3

4

3

5

N

58.3%

4

4

5

4

5

R

61.3%

4

4

2

4

5

Q

62.5%

4

4

2

4

5

D

64.7%

4

5

5

4

5

E

73.1%

5

5

2

4

5

K

81.9%

5

4

2

4

5

Trans.

--

4

8

8

9

4

Ave. range

--

7.0%

16.0%

9.4%

19.9%

11.0%

  1. Ave. range = average range of each reduction group, range is the difference between the maximum and minimum exposed ratio of the AAs of a group.7