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Figure 3 | BMC Bioinformatics

Figure 3

From: Genotyping and inflated type I error rate in genome-wide association case/control studies

Figure 3

(Dependency of Calls) The density of n ( p ˆ A B E [ p ˆ A B ] ) / ( E p ˆ A B E [ p ˆ A B 2 ] ) MathType@MTEF@5@5@+=feaagaart1ev2aaatCvAUfKttLearuWrP9MDH5MBPbIqV92AaeXatLxBI9gBaebbnrfifHhDYfgasaacPC6xNi=xH8viVGI8Gi=hEeeu0xXdbba9frFj0xb9qqpG0dXdb9aspeI8k8fiI+fsY=rqGqVepae9pg0db9vqaiVgFr0xfr=xfr=xc9adbaqaaeGaciGaaiaabeqaaeqabiWaaaGcbaWaaOaaaeaacqWGUbGBaSqabaGccqGGOaakcuWGWbaCgaqcamaaBaaaleaacqWGbbqqcqWGcbGqaeqaaOGaeyOeI0IaemyrauKaei4waSLafmiCaaNbaKaadaWgaaWcbaGaemyqaeKaemOqaieabeaakiabc2faDjabcMcaPiabc+caViabcIcaOiabdweafjqbdchaWzaajaWaaSbaaSqaaiabdgeabjabdkeacbqabaGccqGHsislcqWGfbqrcqGGBbWwcuWGWbaCgaqcamaaDaaaleaacqWGbbqqcqWGcbGqaeaacqaIYaGmaaGccqGGDbqxcqGGPaqkaaa@4BCB@ is compared to a N(0,1) density for 500 subject samples in a quantile-quantile plot. The deviation from the Y = X line indicates that n p ˆ A B MathType@MTEF@5@5@+=feaagaart1ev2aaatCvAUfKttLearuWrP9MDH5MBPbIqV92AaeXatLxBI9gBaebbnrfifHhDYfgasaacPC6xNi=xH8viVGI8Gi=hEeeu0xXdbba9frFj0xb9qqpG0dXdb9aspeI8k8fiI+fsY=rqGqVepae9pg0db9vqaiVgFr0xfr=xfr=xc9adbaqaaeGaciGaaiaabeqaaeqabiWaaaGcbaGaemOBa4MafmiCaaNbaKaadaWgaaWcbaGaemyqaeKaemOqaieabeaaaaa@30F7@ is not distributed as a binomial(n, p AB ) variable.

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