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Table 10 Dispositions of the conventional DC subtypes.

From: An improved ontological representation of dendritic cells as a paradigm for all cell types

  disposition to circulate in the blood disposition to cross-present antigen to CD8+ T cells disposition to migrate to the lymph node disposition to secrete anti- inflammatory cytokines disposition to secrete inflammatory cytokines disposition to secrete type 1 interferon
CD8α-CD11b- DC       
   immature       
   CD8α-CD11b-DC       
   mature     +   
   CD8α-CD11b-DC       
CD8α- CD11b+ DC     +   
   immature     +   
   CD8α- CD11b+DC       
   mature     +   
   CD8α- CD11b+DC       
CD8α + CD11b-DC   +    +  
   immature   +    +  
   CD8α + CD11b-DC       
   mature   +    +  
   CD8α + CD11b-DC       
interstitial DC       
   immature    +    
   interstitial DC       
   mature       
   interstitial DC       
Langerhans cell       
   CD1a+       
   Langerhans cell       
immature    +    
CD1a+       
Langerhans cell       
mature       
CD1a+       
Langerhans cell       
   CD8αlow    +   +  
   Langerhans cell       
immature    +   +  
CD8αlow       
Langerhans cell       
mature    +   +  
CD8αlow       
Langerhans cell       
dermal DC       
   immature    +    
   dermal DC       
   mature dermal DC       
  1. + indicates the cell type referred to by the row label is related to the disposition referred to by the column heading using the has_disposition relation.