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Table 8 Functions of each conventional DC subtype.

From: An improved ontological representation of dendritic cells as a paradigm for all cell types

  antigen processing activity cytokine secretion activity macro- pinocytosis activity T cell antigen presentation activity antigen transportation activity
CD8α-CD11b- DC   +   +  
   immature + + + + +
   CD8α-CD11b- DC      
   mature   +   +  
   CD8α-CD11b- DC      
CD8α- CD11b+ DC   +   +  
   immature + + + + +
   CD8α- CD11b+ DC      
   mature   +   +  
   CD8α- CD11b+ DC      
CD8α + CD11b- DC   +   +  
   immature + + + + +
   CD8α + CD11b- DC      
   mature   +   +  
   CD8α + CD11b- DC      
interstitial DC   +   +  
   immature + + + + +
   interstitial DC      
   mature   +   +  
   interstitial DC      
Langerhans cell   +   +  
   CD1a+ Langerhans cell   +   +  
immature CD1a+ + + + + +
Langerhans cell      
mature CD1a+   +   +  
Langerhans cell      
   CD8αlow Langerhans cell   +   +  
immature CD8αlow + + + + +
Langerhans cell      
mature CD8αlow   +   +  
Langerhans cell      
dermal DC   +   +  
   immature dermal DC + + + + +
   mature dermal DC   +   +  
  1. + indicates that the cell type referred to by the row label is related to the function indicated by the column heading using the has_function relation.