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Table 8 Functions of each conventional DC subtype.

From: An improved ontological representation of dendritic cells as a paradigm for all cell types

 

antigen processing activity

cytokine secretion activity

macro- pinocytosis activity

T cell antigen presentation activity

antigen transportation activity

CD8α-CD11b- DC

 

+

 

+

 

   immature

+

+

+

+

+

   CD8α-CD11b- DC

     

   mature

 

+

 

+

 

   CD8α-CD11b- DC

     

CD8α- CD11b+ DC

 

+

 

+

 

   immature

+

+

+

+

+

   CD8α- CD11b+ DC

     

   mature

 

+

 

+

 

   CD8α- CD11b+ DC

     

CD8α + CD11b- DC

 

+

 

+

 

   immature

+

+

+

+

+

   CD8α + CD11b- DC

     

   mature

 

+

 

+

 

   CD8α + CD11b- DC

     

interstitial DC

 

+

 

+

 

   immature

+

+

+

+

+

   interstitial DC

     

   mature

 

+

 

+

 

   interstitial DC

     

Langerhans cell

 

+

 

+

 

   CD1a+ Langerhans cell

 

+

 

+

 

immature CD1a+

+

+

+

+

+

Langerhans cell

     

mature CD1a+

 

+

 

+

 

Langerhans cell

     

   CD8αlow Langerhans cell

 

+

 

+

 

immature CD8αlow

+

+

+

+

+

Langerhans cell

     

mature CD8αlow

 

+

 

+

 

Langerhans cell

     

dermal DC

 

+

 

+

 

   immature dermal DC

+

+

+

+

+

   mature dermal DC

 

+

 

+

 
  1. + indicates that the cell type referred to by the row label is related to the function indicated by the column heading using the has_function relation.