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Figure 1 | BMC Bioinformatics

Figure 1

From: Gene set-based module discovery in the breast cancer transcriptome

Figure 1

Schema of systematic search for expression modules. We prepared a collection of seed gene sets based on cis-regulatory motifs, ChIP-chip and gene locus information. We next statistically evaluated whether each seed gene set includes a significant large number of coherently expressed genes in expression profile data. If such a coherently expressed gene subset exists, we assumed it as an expression module, and obtained its averaged expression profile as an activity profile.

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