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Table 1 Motif associated with histological grades or prognosis identified based on independent datasets

From: Gene set-based module discovery in the breast cancer transcriptome

Module ID

Size

Z score

The most enriched GO

P value for the most enriched GO

Z score for nearest neighbor pair

Z score for nearest or next to nearest pairs

ETS

47

10.0

immune response

4.55 × 10-15

10.9

9.85

IRF

47

7.59

immune response

6.19 × 10-12

N.S.

3.69

E2F

37

6.67

cell cycle

1.98 × 10-20

32.5

24.5

RUNX

34

5.57

immune response

2.57 × 10-11

12.1

6.08

NFY

30

4.22

cell cycle

9.48 × 10-14

15.4

12.3

NFκ B

29

9.53

immune response

1.51 × 10-7

17.9

4.65

ER

17

9.45

-

-

N.S.

N.S.

PRC2

61

5.87

multicellar organismal development

4.90 × 10-7

N.S.

5.07

8q24

10

7.80

-

-

N.S.

N.S.

17q12

11

7.78

-

-

N.S.

N.S.

  1. N.S. denotes 'not significant'.