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Figure 2 | BMC Bioinformatics

Figure 2

From: Decon2LS: An open-source software package for automated processing and visualization of high resolution mass spectrometry data

Figure 2

The variant of the THRASH algorithm used in Decon2LS: peaks in the mass spectrum are found by comparing their intensity to their shoulders and to the background. Starting at the most intense peak deisotoping is performed by determining charge state, estimating empirical formula, generating a theoretical profile, scoring the theoretical profile and deleting points from the spectrum. This process is continued while peaks of intensity greater than a user specified threshold ratio of the background still exist.

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