From: Analyses of domains and domain fusions in human proto-oncogenes
Num | Pfam accession id | Pfam entry id | Frequency of occurrence in virus proteome | Description of domain family |
---|---|---|---|---|
1 | PF00271 | Helicase_C | 1455 | Helicase conserved C-terminal domain |
2 | PF00023 | Ank | 459 | Ankyrin repeat |
3 | PF00270 | DEAD | 296 | DEAD/DEAH box helicase |
4 | PF00097 | zf-C3HC4 | 168 | Zinc finger, C3HC4 type (RING finger) |
5 | PF00069 | Pkinase | 162 | Protein kinase domain |
6 | PF00001 | 7tm_1 | 115 | 7 transmembrane receptor (rhodopsin family) |
7 | PF00047 | ig | 111 | Immunoglobulin domain |
8 | PF07686 | V-set | 110 | Immunoglobulin V-set domain |
9 | PF00048 | IL8 | 87 | Small cytokines (intecrine/chemokine), interleukin-8 like |
10 | PF00170 | bZIP_1 | 50 | bZIP transcription factor |
11 | PF01403 | Sema | 47 | Sema domain |
12 | PF00167 | FGF | 33 | Fibroblast growth factor |
13 | PF07714 | Pkinase_Tyr | 30 | Protein tyrosine kinase |
14 | PF00096 | zf-C2H2 | 22 | Zinc finger, C2H2 type |
15 | PF00017 | SH2 | 21 | SH2 domain |
16 | PF00560 | LRR_1 | 17 | Leucine Rich Repeat |
17 | PF00018/PF07653 | SH3 | 16 | SH3 domain |
18 | PF00605 | IRF | 16 | Interferon regulatory factor transcription factor |
19 | PF00041 | fn3 | 15 | Fibronectin type III domain |
20 | PF00341 | PDGF | 14 | Platelet-derived growth factor |
21 | PF00452 | Bcl-2 | 12 | Apoptosis regulator proteins, Bcl-2 family |
22 | PF00134 | Cyclin_N | 11 | Cyclin, N-terminal domain |
23 | PF01056 | Myc_N | 11 | Myc amino-terminal region |
24 | PF00010 | HLH | 10 | Helix-loop-helix DNA-binding domain |
25 | PF07679 | I-set | 8 | Immunoglobulin I-set domain |
26 | PF02344 | Myc-LZ | 6 | Myc leucine zipper domain |
27 | PF00076 | RRM_1 | 5 | RNA recognition motif |
28 | PF01437 | PSI | 5 | Plexin repeat |
29 | PF02201 | SWIB | 5 | SWIB/MDM2 domain |
30 | PF00104 | Hormone_recep | 3 | Ligand-binding domain of nuclear hormone receptor |
31 | PF00105 | zf-C4 | 3 | Zinc finger, C4 type |
32 | PF07716 | bZIP_2 | 2 | Basic region leucine zipper |
33 | PF07988 | Wos2 | 2 | Mitotic protein Wos2 |
34 | PF00071 | Ras | 1 | Ras family |
35 | PF00595 | PDZ | 1 | PDZ domain |
36 | PF00611 | FCH | 1 | Fes/CIP4 homology domain |
37 | PF02757 | YLP | 1 | YLP motif |
38 | PF04692 | PDGF_N | 1 | Platelet-derived growth factor, N terminal |