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Figure 7 | BMC Bioinformatics

Figure 7

From: TCP: a tool for designing chimera proteins based on the tertiary structure information

Figure 7

Analysis of the complex structure of a domain of the GM-CSF receptor common beta chain (CB) and the Fab fragment of the monoclonal antibody. A: The complex structure of the CB and the Fab fragment. The heavy chain (1EGJ:H) and light chain (1EGJ:L) of the Fab are coloured green and yellow, respectively. The CB (1EGJ:A) is coloured blue and the residues whose CAs are located within 8 Ã… of the CAs of the Fab are coloured red. B: The colour-coded structure of 1EGJ:A. The black arrow indicates the binding region of the Fab. C: The amino acid sequences of the colour-coded structures shown in B. The asterisks indicate the red-coloured residues in A.

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