Figure 3
From: Statistical and visual differentiation of subcellular imaging
Outlier images. Images that are statistical outliers may be caused by a protein localisation that is distinct from the majority of cells imaged; artefacts in imaging; or an artefact in the generation of the statistics. (a) shows an imaging artefact, perhaps caused contamination of the slide. (b) shows the same image (upper right) in the context of the 3D placement by iCluster of other images of the same class. (c) shows another outlier image found using iCluster. In this case a non-uniform background has caused the automatically generated region of interest selection mask (d) to select non-cellular regions, thus skewing the statistics calculation.