Figure 4
From: Statistical and visual differentiation of subcellular imaging
Distinguishing untreated/treated protein localisation. Two sets of images are visualised in iCluster: one for which the protein SNX1 has been fluorescently tagged and imaged (white borders); and one for which SNX1 has similarly been imaged in cells treated with nocodazole (red borders). For each image, TAS are generated and mapped into 3 dimensions. The visual difference between nocodazole treated and control images is quite subtle with the control images exhibiting slightly more peri-nuclear clustering than the nocodazole treated case. However, the above result of statistic generation and mapping clearly shows that the treated and control images have been distinguished. Each image is shown connected to its nearest neighbour in the 3D space. The top right corner shows the current mouse selected image in more detail.