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Table 1 Design of simulation 1 for evaluation

From: REMAS: a new regression model to identify alternative splicing events from exon array data

Gene ID

Treatment Group

Control Group

1

Exon 5~N (0, 1)

All exons ~N (2.5,1), correlated

 

Exon 6~N (0, 1)

 
 

Others ~N (2.5, 1), correlated

 

2

Exon 5~N (0, 1)

All exons ~N (1.5,1), correlated

 

Exon 6~N (0, 1)

 
 

Others ~N (1.5, 1), correlated

 

3

Exon 5~N (2.5, 1)

Exon 5~N (0, 1)

 

Exon 6~N (0, 1)

Exon 6~N (2.5, 1)

 

Others ~N (2.5, 1), correlated

Others ~N (2.5, 1), correlated

4

Exon 5~N (1.5, 1)

Exon 5~N (0, 1)

 

Exon 6~N (0, 1)

Exon 6~N (1.5, 1)

 

Others ~N (1.5, 1), correlated

Others ~N (1.5, 1), correlated

  1. Exon 5 and Exon 6 are simulated as cassette exons in alternatively spliced gene 1 and 2, while they are defined as mutually exclusive exons in alternatively spliced gene 3 and 4.