Figure 1From: Integrative disease classification based on cross-platform microarray dataDiagram of the integrative disease classification framework. The framework consists of three major steps: (1) Standardization of microarray data and dataset annotation: expression log-rank-ratio vectors were constructed from each microarray data set, and UMLS concepts were extracted from the dataset summary and corresponding MeSH headings. (2) Disease class construction: disease classes were initially constructed by FIM analysis and were further refined by calculating the phenotype distance score. (3) Classification by SVM and ManiSVM.Back to article page