Table 1 Running ModuleDigger in the presence of a gradual increase in noise.
From: ModuleDigger: an itemset mining framework for the detection of cis-regulatory modules
Number of TFs included | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Test set | 10 TFs | 20 TFs | 30 TFs | 40 TFs | ||||||||
Runs | RANK | S | FP | RANK | S | FP | RANK | S | FP | RANK | S | FP |
1 | 6 | y | 1 | 18 | y | 3 | 41 | y | 29 | 15 | y | 12 |
2 | 12 | y | 2 | 9 | y | 2 | 35 | y | 3 | 153 | y | 2 |
3 | 12 | y | 2 | 11 | y | 3 | 45 | y | 39 | 55 | y | 1 |
4 | 11 | y | 3 | 14 | y | 14 | 71 | y | 66 | 54 | y | 9 |
5 | 3 | y | 1 | 12 | y | 1 | 15 | n | 18 | 138 | y | 52 |
6 | 1 | y | 0 | 8 | y | 3 | 38 | y | 1 | 48 | y | 23 |
7 | 1 | y | 0 | 4 | y | 3 | 52 | y | 3 | 141 | y | 49 |
8 | 2 | y | 0 | 6 | y | 3 | 58 | y | 1 | 147 | y | 3 |
9 | 4 | y | 2 | 12 | y | 11 | 32 | y | 1 | 155 | y | 52 |
10 | 1 | y | 0 | 5 | y | 3 | 45 | y | 39 | 158 | y | 81 |
Average | 6.3 | / | 1.1 | 10 | / | 4.5 | 43.2 | / | 20 | 108 | / | 28.4 |
Median | 5 | / | 1 | 10 | / | 3 | 43 | / | 10.5 | 139 | / | 17.5 |
Std | 4.7 | / | 1.1 | 4.3 | / | 4 | 15.2 | / | 22.6 | 56 | / | 28.0 |