Predicting disordered regions in proteins using the profiles of amino acid indices

BMC Bioinformatics

Table 2 The performance DRaai-L on DisProt3.6. The performance of DRaai-L in the independent test on 10% of DisProt3.6 targets under various measures in comparison with other predictors.

Algorithm	Sensitivity	Precision	Specificity	S _product	MCC	S _w
DisEMBL(Coil)	0.71	0.33	0.43	0.31	0.13	0.24
DisEMBL(Rem465)	0.36	0.67	0.93	0.33	0.36	0.29
DisEMBL(Hot Loop)	0.42	0.41	0.77	0.32	0.18	0.19
FoldIndex	0.72	0.46	0.68	0.49	0.36	0.40
IUPred	0.65	0.59	0.82	0.53	0.46	0.47
PONDR(CANXT)	0.41	0.41	0.77	0.32	0.18	0.18
PONDR(VL)	0.55	0.55	0.77	0.42	0.32	0.29
PONDR(VLXT)	0.63	0.45	0.70	0.44	0.30	0.33
PONDR(XL)	0.59	0.37	0.61	0.36	0.18	0.20
VSL2	0.76	0.79	0.79	0.60	0.55	0.55
DRaai-L	0.78	0.80	0.80	0.62	0.58	0.57

ISSN: 1471-2105