Table 4 Lymphoma dataset from [1] (mature aggressive B-cell lymphoma). Mapping of node numbers in Figure 4, the abbreviations used in [1], and the molecular characteristics.
From: On optimal comparability editing with applications to molecular diagnostics
node nr | abbrev. in Jacob et al. | molecular characteristic |
|---|---|---|
1 | CD10 | Antibodies for biomarker CD10 are present in histological section of lymphoma tissue |
2 | Ki-67 | Antibodies for biomarker Ki-67 are present in histological section of lymphoma tissue |
3 | CD5 | Antibodies for biomarker CD5 are present in histological section of lymphoma tissue |
4 | bcl6BR | Breakpoint in the BCL6 locus |
5 | IGH-BCL2 | Fusion of BCL locus to immunoglobulin IGH |
6 | ABC | Gene expression profile similar to activated B-cells |
7 | GCB | Gene expression profile similar to germinal center B-cells |
8 | mBL | Gene expression signature which characterices molecular Burkitt lymphoma (Hummel et al.) |
9 | non-mBL | Absent gene expression signature non-mBL. |
10 | IG-MYC | Translocation of MYC locus involving fusion of MYC to immunoglobulins IGH, IGK or IGL |
11 | atyp.myc | Breakpoint in the MYC locus without fusion to an immunoglobulin |
12 | MYC- | No abberation of the MYC locus |
13 | CD10- | Antibodies for biomarker CD10 are absent in histological section of lymphoma tissue |
14 | Ki-67- | Antibodies for biomarker Ki-67 are absent in histological section of lymphoma tissue |
15 | CD5- | Antibodies for biomarker CD5 are absent in histological section of lymphoma tissue |
16 | bcl6BR- | No breakpoint in the BCL6 locus |
17 | IGH-BCL2- | No fusion of BCL locus to immunoglobulin IGH |