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Table 3 The function of five hub proteins shared by RA and T1D and supporting publications.

From: Identifying disease associations via genome-wide association studies

Protein name Function(GO) Association with RA Association with T1D Pubmed id
HLA class I histocompatibility antigen Immune response Yes Yes 11369787
Radiation-inducible immediate-early gene IEX-1 NOT found in GO Yes Yes 16368886, 14630199
Collagen alpha Integral to membrane; Beta-amyloid binding; Heparin binding Yes No 8816431
Death domain-associated protein 6 Nucleus; Protein binding; Protein homodimerization acitivity; Transcription factor binding No No n/a
Mediator of DNA damage checkpoint protein 1 Nucleus; Protein binding Yes No 17913746