Table 3 The function of five hub proteins shared by RA and T1D and supporting publications.
From: Identifying disease associations via genome-wide association studies
Protein name | Function(GO) | Association with RA | Association with T1D | Pubmed id |
|---|---|---|---|---|
HLA class I histocompatibility antigen | Immune response | Yes | Yes | 11369787 |
Radiation-inducible immediate-early gene IEX-1 | NOT found in GO | Yes | Yes | 16368886, 14630199 |
Collagen alpha | Integral to membrane; Beta-amyloid binding; Heparin binding | Yes | No | 8816431 |
Death domain-associated protein 6 | Nucleus; Protein binding; Protein homodimerization acitivity; Transcription factor binding | No | No | n/a |
Mediator of DNA damage checkpoint protein 1 | Nucleus; Protein binding | Yes | No | 17913746 |