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Figure 2 | BMC Bioinformatics

Figure 2

From: Structuring and extracting knowledge for the support of hypothesis generation in molecular biology

Figure 2

Graphical representation of the biological domain model in OWL and example instances. This proto-ontology contains classes for instances that may be relevant in hypotheses about chromatin (de)condensation. HDAC1 and PCAF are example instances representing proteins implied in models about this process and known to interact. In this and following figures, red diamonds represent instances, dashed arrows connected to diamonds represent instance-of relations and blue dashed arrows represent properties between classes or instances. Inverse relations are not shown for clarity. Protein Association represents the reified relation in which two (or more) proteins participate. Instances of 'BiologicalModel' represent an abstraction of a biological hypothesis that can be partially represented by user queries, proteins provided by the user, and proteins discovered by text mining.

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